Merchant City Medical Group offers surgical and non-surgical cosmetic procedures, from our state of the art clinics throughout the UK & Europe.

Polynucleotides

Improve skin quality from within with polynucleotides (PDRN) treatment at Merchant Medical Group. This advanced injectable therapy uses salmon DNA to stimulate collagen production, repair damaged skin cells, and restore hydration. Rather than adding volume, polynucleotides work at a cellular level to improve texture, firmness, and fine lines, delivering natural-looking results with minimal downtime.

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Procedure overview

KEY INGREDIENTS

High-purity polynucleotides derived from salmon DNA, known for their biocompatibility and exceptional regenerative properties, deeply hydrate and rejuvenate the skin from within.

TREATMENT AREAS

Face, neck, décolletage, and hands—addressing skin laxity, fine lines, and signs of ageing to restore a youthful appearance.

IDEAL FOR

Individuals noticing early to advanced signs of ageing or those seeking to improve skin texture, elasticity, and hydration.

PRODUCTS USED

Plinest, Plinest Eye and Newest

SUITABILITY

Suitable for adults across various age groups, excluding pregnant or breastfeeding women and those with certain medical conditions.

PROCEDURE TIME

A course of three sessions spaced three weeks apart, each lasting around 30 minutes. Maintenance sessions may be recommended every 6 to 12 months.

Treatments

Polynucleotide therapy at Merchant Medical Group revitalises the skin by stimulating natural cellular regeneration. This advanced injectable treatment uses biocompatible DNA fragments to activate collagen and elastin production, improving skin firmness, elasticity, and hydration. Delivered through precise micro-injections with minimal discomfort, polynucleotides work over around 28 days to repair and strengthen the skin from within, creating a natural lifting and tightening effect that goes beyond conventional skin treatments.

Commonly Asked Questions

Polynucleotide Therapy is an injectable treatment that rejuvenates and repairs the skin from within by stimulating collagen and elastin production. Unlike fillers, it improves skin quality at a cellular level rather than adding volume.

Suitable for adults noticing fine lines, loss of firmness, or dull skin. It can be used both preventatively and to revitalise more mature skin.

Common areas include the face, neck, décolletage, and hands—areas most affected by ageing and environmental exposure.

A typical course involves three sessions spaced around three weeks apart. Each session lasts about 30 minutes and is minimally uncomfortable, usually without the need for anaesthetic.

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There is little to no downtime. Mild redness or swelling may occur and usually settles within a few days. Avoid strenuous exercise, heat, and direct sun exposure for 48 hours.

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Results typically last 6–12 months, with improvements developing gradually. Long-term benefits include better skin texture, elasticity, and overall skin health. Maintenance treatments help sustain results.

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Treatments are available at Merchant Medical Group. Choose a provider with experienced practitioners, thorough consultations, and personalised treatment plans for safe, effective results.

 

Excellence Record

Merchant City Medical Group is proud to be one of the leading providers of Hair Transplant Surgeries and Medical Aesthetics within the UK and Europe. With our extensive team of expert surgeons, nurse practitioners and consultants, you will be met with the utmost dedication and compassion throughout your journey with us.
  • 30+ Years of combined experience
  • 10 + Experts
  • 1000 + Satisfied Patients

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Cosmetic Procedure Screening Questionnaire

It can be used as a screening questionnaire to tell whether you might have BDD.

1) How often do you do you deliberately check your feature(s)? Not accidentally catch sight of it. Please include looking at your feature in a mirror or other reflective surfaces like a shop window or looking at it directly or feeling it with your fingers.
2) To what extent do you feel your feature(s) are currently ugly, unattractive or ‘not right’?
3) To what extent does your feature(s) currently cause you a lot of distress?
4) How often does your feature(s) currently lead you to avoid situations or activities?
5) To what extent does your feature(s) currently preoccupy you? That is, you think about it a lot and it is hard to stop thinking about it?
6) If you have a partner, to what extent does your feature(s) currently have an effect on your relationship with an existing partner? (e.g. affectionate feelings, number of arguments, enjoying activities together). If you do not have a partner, to what extent does your feature(s) currently have an effect on dating or developing a relationship?
7) To what extent does your feature(s) currently interfere with your ability to work or study, or your role as a homemaker? (Please rate this even if you are not working or studying: we are interested in your ability to work or study.)
8) To what extent does your feature(s) currently interfere with your social life? (with other people, e.g. parties, pubs, clubs, outings, visits, home entertainment)
9) To what extent, do you feel your appearance is the most important aspect of who you are?

Do I have BDD?

Body Dysmorphic Disorder

You have scored 0

When you score more than 40 points, this is an indication that you likely have Body Dysmorphic Disorder. However, this is not a formal diagnosis. This test can also be used after a treatment to see if symptoms have improved.

What now?

For more information on BDD and support, you can contact us.

If you are a UK resident, we suggest:

    • reaching out to your GP for more help
    • self-refer to NHS Talking Therapies.

When speaking to a health professional, you may present your clinic history or a printed form to clearly outline the symptoms you’ve experienced.